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Ciclosporin Plus MTX May Offer Option for Psoriatic Arthritis: Study
NEW YORK (Reuters Health) May 23 - In patients with active psoriatic arthritis who have an inadequate response to methotrexate (MTX) treatment, the addition of ciclosporin A (CSA; cyclosporine) may offer "clinically important benefits," UK researcher... [ More ]

Magnesium Ion Helps Suppress Rheumatoid Arthritis Development
Tokyo (JCNN) - Japanese salt manufacturer Akokasei has announced the results of its latest research on brine water that richly contains magnesium ion (Mg2+).

In its recent experiments on rats with adjuvant arthritis (AA), the company examined... [ More ]

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Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis
Introduction

In cancer the gelatinases matrix metalloproteinase (MMP)-2 and MMP-9 have been shown to be associated with tissue invasion and metastatic disease. In patients with inflammatory arthritis the gelatinases are expressed in the... [ More ]

Acute-phase serum amyloid A production by rheumatoid arthritis synovial tissue
Introduction:
Serum amyloid A (SAA) is the circulating precursor of amyloid A protein, the fibrillar component of amyloid deposits. In humans, four SAA genes have been described. Two genes (SAA1 and SAA2) encode A-SAA and are coordinately induced ... [ More ]

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